SCHEMBL1491201

SCHEMBL1491201

CCCC(C)C(=O)Nc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.69
TSHR P16473 1/20 0.69
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
CA7 P43166 1/20 0.63
CA14 Q9ULX7 1/20 0.63
MME P08473 1/20 0.59
ACE P12821 1/20 0.59
KDM4E B2RXH2 1/20 0.55
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
ALDH1A1 P00352 3/20 0.54
MAPT P10636 3/20 0.54
LMNA P02545 1/20 0.54
GAA P10253 1/20 0.54
ATM Q13315 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
MAPK1 P28482 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
NPC1 O15118 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28855894 0.90 ALDH1A1 (0.62) HSD17B10TSHRCA1CA2CA7
SCHEMBL11877345 0.89 HSD17B10 (0.74) HSD17B10TSHRCA1CA2CA7
SCHEMBL11659676 0.88 ALDH1A1 (0.61) HSD17B10TSHRCA1CA2CA7
SCHEMBL11869914 0.87 HSD17B10 (0.71) HSD17B10TSHRCA1CA2CA7
SCHEMBL20353846 0.87 HDAC8 (0.58) HSD17B10TSHRMMEACEMEN1
SCHEMBL11515231 0.87 HDAC8 (0.58) HSD17B10TSHRMMEACEMEN1
SCHEMBL31290862 0.86 MME (0.59) HSD17B10TSHRCA1CA2CA7
SCHEMBL10067641 0.86 MME (0.59) HSD17B10TSHRCA1CA2CA7
SCHEMBL12205972 0.85 MME (0.63) HSD17B10CA1CA2CA7CA14
SCHEMBL18456226 0.85 MME (0.63) HSD17B10CA1CA2CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011084492-A1 TRASH BAG WITH MALODOR CONTROL THE GLAD PRODUCTS COMPANY (US) 2011-07-14 WO claimed
EP-1029032-B1 LAUNDRY TREATMENT PRODUCTS FOR SPANDEX CONTAINING FABRICS UNILEVER PLC (GB) 2004-03-03 EP claimed
CN-109561680-B Small molecule modulators of pantothenate kinase 圣朱德儿童研究医院 2021-07-13 CN disclosed
CN-111787939-A Methods of treating CASTOR-associated diseases 圣朱德儿童研究医院有限公司 2020-10-16 CN disclosed
US-10640461-B2 Heterodimers of glutamic acid MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2020-05-05 US disclosed
US-10570153-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2020-02-25 US disclosed
US-9814722-B2 Heteroaryl substituted pyrrolo[2,3-B] pyridines and pyrrolo[2,3-B] pyrimidines as janus kinase inhibitors INCYTE HOLDINGS CORPORATION (US) 2017-11-14 US disclosed
EP-2160445-B1 Method for preparing non-textile polymer article INVISTA TECHNOLOGIES SARL (CH) 2017-03-22 EP disclosed
US-9328190-B2 Non-textile polymer compositions and methods INVISTA NORTH AMERICA S.A.R.L. (US) 2016-05-03 US disclosed
US-20140357730-A1 NON-TEXTILE POLYMER COMPOSITIONS AND METHODS INVISTA North America S.à r.l. (US) 2014-12-04 US disclosed
US-8048843-B2 Fabric care compositions INVISTA North America S.à.r.l. (US) 2011-11-01 US disclosed
US-6713410-B1 DEPOSITING A PERFUME MIXTURE WHICH PREFERENTIALLY DEPOSIT ON SPANDEX FIBERS AND IS RETAINED BETTER THAN ON OTHER TEXTILE FIBERS; WASHING; DEODORANT E.I. DU PONT DE NEMOURS AND CO. 2004-03-30 US disclosed
EP-1029032-B1 LAUNDRY TREATMENT PRODUCTS FOR SPANDEX CONTAINING FABRICS UNILEVER PLC (GB) 2004-03-03 EP disclosed
US-6465420-B1 YARN OR FABRIC COMPRISING COTTON AND SPANDEX FIBRES, HAVING A PERFUME COMPOSITION DEPOSITED ON THE SAID YARN OR FABRIC QUEST INTERNATIONAL B.V. (NL) 2002-10-15 US disclosed
EP-1029032-A1 LAUNDRY TREATMENT PRODUCTS FOR SPANDEX CONTAINING FABRICS UNILEVER PLC (GB) 2000-08-23 EP disclosed
EP-1023480-A1 METHOD FOR TEXTILE TREATMENT FOR SPANDEX CONTAINING FABRICS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2000-08-02 EP disclosed
EP-1021160-A1 PERFUME COMPOSITIONS QUEST INTERNATIONAL NEDERLAND BV (NL) 2000-07-26 EP disclosed
WO-1999019452-A1 LAUNDRY TREATMENT PRODUCTS FOR SPANDEX® CONTAINING FABRICS UNILEVER PLC (GB) 1999-04-22 WO disclosed
WO-1999019553-A1 METHOD FOR TEXTILE TREATMENT FOR SPANDEX CONTAINING FABRICS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-04-22 WO disclosed
WO-1999018926-A1 PERFUME COMPOSITIONS QUEST INTERNATIONAL B.V. (NL) 1999-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10570153-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 HSD17B10 890/4885TSHR 1396/4885CA1 2430/4885
US-10640461-B2 Heterodimers of glutamic acid DDO, GLUL, ASNS HSD17B10 585/4885TSHR 1266/4885CA1 72/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.