SCHEMBL9761757

SCHEMBL9761757

CC1CC(=O)CC(=O)C1(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.33
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2693191 0.81
SCHEMBL15657312 0.72 CRBN (0.35) CRBNMAPTALDH1A1
SCHEMBL15659906 0.68 CRBN (0.32) CRBNMAPTMEN1ALDH1A1LMNA
SCHEMBL634197 0.67
SCHEMBL6869846 0.67
SCHEMBL23645791 0.67
SCHEMBL28158431 0.65 PTPN1 (0.35) CRBNMAPTALDH1A1PTPN1
SCHEMBL10507213 0.65 MAPT (0.50) MAPTALDH1A1
SCHEMBL351712 0.64
SCHEMBL28863276 0.64 CYP1A2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4937386-A BY REACTING 4,4,5-TRIMETHYLCYCLOHEXANE-1,3-DIONE AND 2-NITRO-4-METHYL SULFONYL BENZOYL CHLORIDE; HERBICIDES NIPPON SODA CO., LTD. (JP) 1990-06-26 US claimed
JP-3209362-A None JP disclosed
JP-3209361-A None JP disclosed
JP-2019355-A None JP disclosed
EP-3350296-A1 PERFUME COMPOSITION COMPRISING AN ODOR MODULATOR COMPOUND, AMINO ALCOHOL AND ODORIFEROUS ALDEHYDE AND/OR ODORIFEROUS KETONE FOR INCREASING AND PROLONGING ODOR INTENSITY Henkel AG & Co. KGaA (DE) 2018-07-25 EP disclosed
CN-105037282-A Triazolyl pinacolone purification method ZHANGJIAGANG CITY ZHENFANG CHEMICAL CO LTD 2015-11-11 CN disclosed
CN-105037118-A Pinacolone preparation method ZHANGJIAGANG CITY ZHENFANG CHEMICAL CO LTD 2015-11-11 CN disclosed
CN-104961634-A Method for preparing high yield pinacolone, and pesticide bactericide ZHANGJIAGANG CITY ZHENFANG CHEMICAL CO LTD 2015-10-07 CN disclosed
JP-H03209362-A 4,4,5-TRIMETHYL-2-(2,3-DIMETHYL-4-METHYLSULFONYLBENZOLY) CYCLOHEXANE-1,3-DIONE, PRODUCTION THEREOF AND USE AS HERBICIDE NIPPON SODA CO LTD 1991-09-12 JP disclosed
JP-H03209361-A 4,4,5-TRIMETHYL-2-(2-CHLORO-3-METHOXY-4-METHYLSULFONYLBENZOYL)CYCLOHEXANE-1,3-DIONE, PRODUCTION THEREOF AND HERBICIDE NIPPON SODA CO LTD 1991-09-12 JP disclosed
US-4937386-A BY REACTING 4,4,5-TRIMETHYLCYCLOHEXANE-1,3-DIONE AND 2-NITRO-4-METHYL SULFONYL BENZOYL CHLORIDE; HERBICIDES NIPPON SODA CO., LTD. (JP) 1990-06-26 US disclosed
JP-H0219355-A 4,4,5-TRIMETHYL-2-(2-NITRO-4-METHYLSULFONYLBENZOYL)CYC-LOHEXANE-1,3-DIONE, PRODUCTION THEREOF AND HERBICIDE NIPPON SODA CO LTD 1990-01-23 JP disclosed
EP-0061669-B1 PROCESS FOR THE PREPARATION OF CYCLOHEXANE-1,3-DIONES, AND SOME BICYCLIC CYCLOHEXANE-1,3-DIONES BASF Aktiengesellschaft (DE) 1984-07-25 EP disclosed
EP-0061669-A1 Process for the preparation of cyclohexane-1,3-diones, and some bicyclic cyclohexane-1,3-diones BASF Aktiengesellschaft (DE) 1982-10-06 EP disclosed