Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29306459 | 0.79 | EPHX2 (0.39) | JMJD6EPHX2NPC1RAB9AOPRM1 | |
| SCHEMBL23986458 | 0.78 | EPHX2 (0.38) | JMJD6EPHX2OPRM1OPRL1DDB1 | |
| SCHEMBL24792887 | 0.76 | EPHX2 (0.42) | JMJD6EPHX2OPRM1OPRL1DDB1 | |
| SCHEMBL9762587 | 0.75 | EPHX2 (0.36) | EPHX2OPRM1OPRL1DDB1CRBN | |
| SCHEMBL2629338 | 0.75 | — | — | |
| SCHEMBL1913020 | 0.75 | EPHX2 (0.41) | JMJD6EPHX2OPRM1OPRL1DDB1 | |
| SCHEMBL17541290 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL10815720 | 0.72 | EPHX2 (0.39) | EPHX2OPRM1OPRL1DDB1CRBN | |
| SCHEMBL18355383 | 0.70 | EPHX2 (0.38) | EPHX2OPRM1OPRL1DDB1CRBN | |
| SCHEMBL17662643 | 0.70 | JMJD6 (0.43) | JMJD6KDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045783-A | Diaza class anti-allergy medicament | PFIZER (US) | 1990-10-03 | — | — | CN | claimed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | disclosed |
| CN-1045783-A | Diaza class anti-allergy medicament | PFIZER (US) | 1990-10-03 | — | — | CN | disclosed |