Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2629338 | 0.83 | — | — | |
| SCHEMBL15884724 | 0.79 | EPHX2 (0.42) | EPHX2KCNH2CYP19A1DDB1CRBN | |
| SCHEMBL9761835 | 0.75 | JMJD6 (0.39) | EPHX2KCNH2CYP19A1DDB1CRBN | |
| Hydrochloric Acid SCHEMBL10815720 | 0.72 | EPHX2 (0.39) | EPHX2KCNH2CYP19A1DDB1CRBN | |
| SCHEMBL28025119 | 0.71 | DGAT1 (0.42) | DDB1CRBNKMT2AHDAC1HDAC6 | |
| SCHEMBL23986458 | 0.70 | EPHX2 (0.38) | EPHX2KCNH2CYP19A1DDB1CRBN | |
| SCHEMBL18355383 | 0.70 | EPHX2 (0.38) | EPHX2KCNH2CYP19A1DDB1CRBN | |
| SCHEMBL7661242 | 0.69 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL18483946 | 0.68 | DDB1 (0.38) | EPHX2KCNH2CYP19A1DDB1CRBN | |
| SCHEMBL19075349 | 0.68 | HDAC1 (0.42) | EPHX2KCNH2DDB1CRBNGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | claimed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | disclosed |