Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PAM | P19021 | 2/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763198 | 0.82 | TSHR (0.43) | TSHRLMNAALDH1A1GAADGKA | |
| SCHEMBL9147241 | 0.80 | CYP1A2 (0.48) | TSHRALDH1A1GAADGKACYP3A4 | |
| SCHEMBL9762017 | 0.79 | TSHR (0.45) | TSHRLMNAALDH1A1GAADGKA | |
| SCHEMBL491650 | 0.77 | TSHR (0.50) | TSHRLMNAALDH1A1DGKACYP3A4 | |
| SCHEMBL15380707 | 0.77 | TSHR (0.50) | TSHRLMNAALDH1A1DGKACYP3A4 | |
| SCHEMBL8752652 | 0.77 | TSHR (0.50) | TSHRLMNAALDH1A1DGKACYP3A4 | |
| SCHEMBL8752681 | 0.77 | TSHR (0.50) | TSHRLMNAALDH1A1DGKACYP3A4 | |
| SCHEMBL15566 | 0.77 | TSHR (0.50) | TSHRLMNAALDH1A1DGKACYP3A4 | |
| SCHEMBL20564136 | 0.77 | TSHR (0.50) | TSHRLMNAALDH1A1DGKACYP3A4 | |
| SCHEMBL29912563 | 0.77 | TSHR (0.50) | TSHRLMNAALDH1A1DGKACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000881-A | Polymerizable organosilane compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-03-19 | — | — | US | claimed |
| US-5000881-A | Polymerizable organosilane compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-03-19 | — | — | US | disclosed |