SCHEMBL15566

SCHEMBL15566

C=COC(=O)CCCCCCCCCCCCCCCCC(=O)OC=C

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.50
LMNA P02545 4/20 0.48
ALDH1A1 P00352 4/20 0.48
MAPT P10636 2/20 0.39
ABCC4 O15439 1/20 0.39
DGKA P23743 1/20 0.38
CYP3A4 P08684 2/20 0.36
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
PAM P19021 2/20 0.34
EPHX2 P34913 1/20 0.33
MAPK1 P28482 1/20 0.33
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27836685 1.00 TSHR (0.50) TSHRLMNAALDH1A1MAPTABCC4
SCHEMBL328704 1.00 TSHR (0.50) TSHRLMNAALDH1A1MAPTABCC4
SCHEMBL491383 1.00 TSHR (0.50) TSHRLMNAALDH1A1MAPTABCC4
SCHEMBL15380707 1.00 TSHR (0.50) TSHRLMNAALDH1A1MAPTABCC4
SCHEMBL8752681 1.00 TSHR (0.50) TSHRLMNAALDH1A1MAPTABCC4
SCHEMBL29912563 1.00 TSHR (0.50) TSHRLMNAALDH1A1MAPTABCC4
SCHEMBL8752652 1.00 TSHR (0.50) TSHRLMNAALDH1A1MAPTABCC4
SCHEMBL491650 1.00 TSHR (0.50) TSHRLMNAALDH1A1MAPTABCC4
SCHEMBL20564136 1.00 TSHR (0.50) TSHRLMNAALDH1A1MAPTABCC4
SCHEMBL15869 1.00 TSHR (0.50) TSHRLMNAALDH1A1MAPTABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 363 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4367220-A COMPOSED OF LIPOSOLUBLE VINYL ESTER POLYMER UNITS, 1-DOCOSANOYLOXY-3-(2-ETHYL)-HEXYLOXY-2-PROPANOL, FAT AND COLORING MATERIAL L'OREAL (FR) 1983-01-04 US claimed
US-20260090973-A1 EYE KERATIN MATERIAL COATING COMPOSITIONS L'OREAL (FR) 2026-04-02 US disclosed
US-20260090971-A1 EYE KERATIN MATERIAL COATING COMPOSITIONS L'OREAL (FR) 2026-04-02 US disclosed
US-20260090972-A1 EYE KERATIN MATERIAL COATING COMPOSITIONS L'OREAL (FR) 2026-04-02 US disclosed
US-12551431-B2 Peel-off film-forming cosmetic composition CHANEL PARFUMS BEAUTE (FR) 2026-02-17 US disclosed
EP-4661971-A1 COSMETIC COMPOSITION COMPRISING HYDROPHOBIC AND HYDROPHILIC TREATED PIGMENTS Chanel Parfums Beauté (FR) 2025-12-17 EP disclosed
US-12472128-B2 Long-lasting solid cosmetic composition CHANEL PARFUMS BEAUTE (FR) 2025-11-18 US disclosed
US-20250195390-A1 EYELASH COATING COMPOSITIONS FOR FALSE EYELASHES L'OREAL (FR) 2025-06-19 US disclosed
US-12239209-B2 System for dispensing a cosmetic product L'OREAL (FR) 2025-03-04 US disclosed
US-12171861-B2 Long-lasting cosmetic composition CHANEL PARFUMS BEAUTE (FR) 2024-12-24 US disclosed
US-20020189030-A1 Use of a polymer for obtaining an express make-up of keratin materials COLLIN NATHALIE (FR) 2002-12-19 US disclosed
US-20020192251-A1 Mascara; containing cellulose fiber mixtures L'OREAL (FR) 2002-12-19 US disclosed
US-20020098217-A1 Cosmetic composition comprising at least one fiber and at least one wax PIOT BERTRAND (FR) 2002-07-25 US disclosed
WO-2002049583-A1 COSMETIC COMPOSITION COMPRISING A POLYMER AND FIBRES L'OREAL S.A. (FR) 2002-06-27 WO disclosed
WO-2002047619-A2 COSMETIC COMPOSITION COMPRISING A POLYMER AND FIBRES L'OREAL S.A. (FR) 2002-06-20 WO disclosed
US-20020051759-A1 Film -forming cosmetic composition EVONIK OPERATIONS GMBH (DE) 2002-05-02 US disclosed
US-20020044917-A1 Film-forming cosmetic composition DE LA POTERIE VALERIE (FR) 2002-04-18 US disclosed
US-20020041857-A1 Film-forming cosmetic composition EVONIK DEGUSSA GMBH (DE) 2002-04-11 US disclosed
US-20010006665-A1 Composition comprising at least one wax and at least one oil L'OREAL S.A. (FR) 2001-07-05 US disclosed
US-4367220-A COMPOSED OF LIPOSOLUBLE VINYL ESTER POLYMER UNITS, 1-DOCOSANOYLOXY-3-(2-ETHYL)-HEXYLOXY-2-PROPANOL, FAT AND COLORING MATERIAL L'OREAL (FR) 1983-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260090971-A1 EYE KERATIN MATERIAL COATING COMPOSITIONS KRT18, AQP3, SMC3 TSHR 1990/4885LMNA 716/4885ALDH1A1 3702/4885
US-20020189030-A1 Use of a polymer for obtaining an express make-up of keratin materials KRT18, FABP4, EPCAM TSHR 4619/4885LMNA 1378/4885ALDH1A1 2477/4885
US-20020051759-A1 Film -forming cosmetic composition KRT18, CUTA, DSG1 TSHR 2076/4885LMNA 1255/4885ALDH1A1 1967/4885
US-20020098217-A1 Cosmetic composition comprising at least one fiber and at least one wax KRT18, CUTA, DSG1 TSHR 4605/4885LMNA 388/4885ALDH1A1 478/4885
US-12239209-B2 System for dispensing a cosmetic product PDE12, SAMM50, POLR1C TSHR 1719/4885LMNA 3121/4885ALDH1A1 1324/4885
US-20010006665-A1 Composition comprising at least one wax and at least one oil CUTA, COL14A1, LIPA TSHR 4641/4885LMNA 773/4885ALDH1A1 2880/4885
US-20020044917-A1 Film-forming cosmetic composition RTF1, RCOR3, AQP3 TSHR 2048/4885LMNA 2825/4885ALDH1A1 2704/4885
US-20020041857-A1 Film-forming cosmetic composition KRT18, CUTA, KAT8 TSHR 1559/4885LMNA 1368/4885ALDH1A1 3114/4885
US-20260090973-A1 EYE KERATIN MATERIAL COATING COMPOSITIONS KRT18, SMC3, MARK3 TSHR 1608/4885LMNA 1069/4885ALDH1A1 2113/4885
US-20260090972-A1 EYE KERATIN MATERIAL COATING COMPOSITIONS KRT18, SMC3, MARK3 TSHR 1835/4885LMNA 1517/4885ALDH1A1 3101/4885
US-12472128-B2 Long-lasting solid cosmetic composition CUTA, AUP1, LIPA TSHR 1997/4885LMNA 747/4885ALDH1A1 1718/4885
US-12551431-B2 Peel-off film-forming cosmetic composition CUTA, KRT18, DSG1 TSHR 1721/4885LMNA 303/4885ALDH1A1 1971/4885
US-12171861-B2 Long-lasting cosmetic composition KRT18, CUTA, COL14A1 TSHR 3212/4885LMNA 330/4885ALDH1A1 2867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.