Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800407 | 0.89 | TSHR (0.47) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL17315368 | 0.84 | CA1 (0.68) | CA1CA2CA12CA9 | |
| SCHEMBL14240063 | 0.82 | CA2 (0.49) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL13157202 | 0.81 | TSHR (0.50) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL13439294 | 0.81 | CA1 (0.60) | CA1CA2CA12CA9 | |
| SCHEMBL11748511 | 0.80 | MAPT (0.52) | CA1CA2CA12CA9PRSS1 | |
| SCHEMBL11149031 | 0.79 | CA1 (0.46) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL17315152 | 0.79 | CA2 (0.48) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL10759252 | 0.78 | EDNRA (0.48) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL7759383 | 0.77 | TDP1 (0.43) | CA1CA2CA12CA9PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003052-A | Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0208655-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1990-08-16 | — | — | EP | disclosed |