SCHEMBL9762352

SCHEMBL9762352

C=CCOC(C)(C)C(=O)c1ccc2c(c1)c1ccccc1n2C

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.53
HPGD P15428 7/20 0.43
ALDH1A1 P00352 6/20 0.43
RORC P51449 1/20 0.42
NPY5R Q15761 1/20 0.41
MAPT P10636 3/20 0.40
HSD17B10 Q99714 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
POLB P06746 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 1/20 0.39
CNR2 P34972 1/20 0.39
PTGER4 P35408 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9761164 0.81 KDM4E (0.62) KDM4EHPGDALDH1A1RORCNPY5R
SCHEMBL9761569 0.77 KDM4E (0.68) KDM4EHPGDALDH1A1RORCNPY5R
SCHEMBL10384389 0.75 CYP3A4 (0.42) HPGDALDH1A1HSD17B10MEN1KMT2A
SCHEMBL10943793 0.73 KDM4E (0.51) KDM4EHPGDALDH1A1MAPTHSD17B10
SCHEMBL10945099 0.73 KDM4E (0.51) KDM4EHPGDALDH1A1NPY5RMAPT
SCHEMBL10943054 0.73 ELANE (0.47) HPGDALDH1A1LMNA
SCHEMBL9762591 0.71 KDM4E (0.52) KDM4EHPGDALDH1A1RORCNPY5R
SCHEMBL2026269 0.71 KDM4E (0.76) KDM4EHPGDALDH1A1RORCNPY5R
SCHEMBL29643237 0.71 KDM4E (0.76) KDM4EHPGDALDH1A1RORCNPY5R
SCHEMBL30850787 0.71 KDM4E (1.00) KDM4EHPGDALDH1A1RORCNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5071888-A Storage stability ASAHI DENKA KOGYO K.K. (JP) 1991-12-10 US disclosed
EP-0171600-B1 CARBAZOLE PHOTOINITIATORS FOR THE PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1991-06-12 EP disclosed
EP-0171600-A1 Carbazole photoinitiators for the photopolymerization of unsaturated compounds ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1986-02-19 EP disclosed