SCHEMBL9762382

SCHEMBL9762382

CCCCCCCCc1ccccc1OC(=O)c1ccc(-c2ccc(C(C)OC)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.50
THRB P10828 1/20 0.50
PPARA Q07869 2/20 0.43
NPSR1 Q6W5P4 1/20 0.42
RARB P10826 5/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
RARA P10276 1/20 0.41
MTOR P42345 1/20 0.41
KMT2A Q03164 1/20 0.41
PPARG P37231 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
ALOX5 P09917 1/20 0.39
PTGS2 P35354 1/20 0.39
PRSS1 P07477 1/20 0.37
ACR P10323 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
ADRB2 P07550 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9761542 1.00 THRA (0.50) THRATHRBPPARANPSR1RARB
SCHEMBL9760315 1.00 THRA (0.50) THRATHRBPPARANPSR1RARB
SCHEMBL9760952 1.00 THRA (0.50) THRATHRBPPARANPSR1RARB
SCHEMBL9762146 0.97 THRA (0.53) THRATHRBPPARANPSR1PPARG
SCHEMBL9760479 0.97 THRA (0.53) THRATHRBPPARANPSR1PPARG
SCHEMBL9761271 0.97 THRA (0.53) THRATHRBPPARANPSR1PPARG
SCHEMBL9760534 0.97 THRA (0.53) THRATHRBPPARANPSR1PPARG
SCHEMBL9761298 0.96 NPSR1 (0.44) THRATHRBPPARANPSR1RARB
SCHEMBL9761024 0.92 NPSR1 (0.46) THRATHRBPPARANPSR1MEN1
SCHEMBL9761604 0.91 NPSR1 (0.46) THRATHRBPPARANPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297745-B1 OPTICALLY ACTIVE ETHER DERIVATIVES, PREPARATION PROCESSES THEREFOR, LIQUID CRYSTAL MATERIALS AND AN OPTICAL SWITCHING ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-09-18 EP disclosed
US-5013479-A Aromatic ether esters containing two or three benzene rings SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-07 US disclosed
EP-0297745-A1 Optically active ether derivatives, preparation processes therefor, liquid crystal materials and an optical switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-01-04 EP disclosed