Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | ACR | P10323 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760875 | 1.00 | LMNA (0.51) | LMNACYP1A2CYP2C19NPC1CYP2C9 | |
| SCHEMBL9761886 | 0.96 | MAPT (0.54) | LMNACYP1A2CYP2C19NPC1CYP2C9 | |
| SCHEMBL9762286 | 0.96 | MAPT (0.54) | LMNACYP1A2CYP2C19NPC1CYP2C9 | |
| SCHEMBL9761946 | 0.96 | MAPT (0.54) | LMNACYP1A2CYP2C19NPC1CYP2C9 | |
| SCHEMBL9760669 | 0.96 | MAPT (0.54) | LMNACYP1A2CYP2C19NPC1CYP2C9 | |
| SCHEMBL9761635 | 0.96 | LMNA (0.56) | LMNACYP1A2CYP2C19NPC1CYP2C9 | |
| SCHEMBL9761461 | 0.93 | LMNA (0.50) | LMNACYP1A2CYP2C19NPC1CYP2C9 | |
| SCHEMBL9761195 | 0.93 | LMNA (0.50) | LMNACYP1A2CYP2C19NPC1CYP2C9 | |
| SCHEMBL9761747 | 0.93 | LMNA (0.59) | LMNACYP1A2CYP2C19NPC1CYP2C9 | |
| SCHEMBL9761970 | 0.92 | NPC1 (0.62) | LMNACYP1A2CYP2C19NPC1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297745-B1 | OPTICALLY ACTIVE ETHER DERIVATIVES, PREPARATION PROCESSES THEREFOR, LIQUID CRYSTAL MATERIALS AND AN OPTICAL SWITCHING ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-5013479-A | Aromatic ether esters containing two or three benzene rings | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0297745-A1 | Optically active ether derivatives, preparation processes therefor, liquid crystal materials and an optical switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-01-04 | — | — | EP | disclosed |