SCHEMBL9762585

SCHEMBL9762585

CC(O)N(C(C)O)C(C)(C)C(=O)c1ccc2c(c1)c1ccccc1n2C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.57
ALDH1A1 P00352 7/20 0.44
HPGD P15428 7/20 0.44
NPY5R Q15761 1/20 0.43
RORC P51449 1/20 0.42
MAPT P10636 5/20 0.40
GPR3 P46089 1/20 0.40
CNR2 P34972 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 2/20 0.40
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
POLB P06746 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9761569 0.80 KDM4E (0.68) KDM4EALDH1A1HPGDNPY5RRORC
SCHEMBL9761164 0.76 KDM4E (0.62) KDM4EALDH1A1HPGDNPY5RRORC
SCHEMBL9762591 0.76 KDM4E (0.52) KDM4EALDH1A1HPGDNPY5RRORC
SCHEMBL10944265 0.76 KDM4E (0.51) KDM4EALDH1A1HPGDNPY5RRORC
SCHEMBL10945675 0.76 KDM4E (0.51) KDM4EALDH1A1HPGDNPY5RMAPT
SCHEMBL9760859 0.76 KDM4E (0.69) KDM4EALDH1A1HPGDNPY5RRORC
SCHEMBL2026269 0.73 KDM4E (0.76) KDM4EALDH1A1HPGDNPY5RRORC
SCHEMBL29643237 0.73 KDM4E (0.76) KDM4EALDH1A1HPGDNPY5RRORC
SCHEMBL30850787 0.73 KDM4E (1.00) KDM4EALDH1A1HPGDNPY5RRORC
SCHEMBL3102894 0.73 KDM4E (1.00) KDM4EALDH1A1HPGDNPY5RRORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5071888-A Storage stability ASAHI DENKA KOGYO K.K. (JP) 1991-12-10 US disclosed
EP-0171600-B1 CARBAZOLE PHOTOINITIATORS FOR THE PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1991-06-12 EP disclosed
EP-0171600-A1 Carbazole photoinitiators for the photopolymerization of unsaturated compounds ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1986-02-19 EP disclosed