Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16005641 | 0.84 | ELANE (0.51) | KDM4EALDH1A1 | |
| SCHEMBL909309 | 0.84 | KDM4E (0.56) | KDM4ECA12CA9MAPTMAPK1 | |
| SCHEMBL4186794 | 0.83 | KDM4E (0.50) | KDM4ECA12CA9MAPTMAPK1 | |
| SCHEMBL2099558 | 0.80 | PTPN1 (0.57) | KDM4EMAPTMAPK1GAAALDH1A1 | |
| SCHEMBL30595409 | 0.78 | CA12 (0.65) | KDM4ECA12CA9MAPTGLA | |
| SCHEMBL3974361 | 0.78 | CA12 (0.65) | KDM4ECA12CA9MAPTGLA | |
| SCHEMBL6441929 | 0.77 | KDM4E (0.69) | KDM4EMAPTMAPK1GLAGAA | |
| SCHEMBL4360840 | 0.77 | KDM4E (0.73) | KDM4EMAPTMAPK1GAAALDH1A1 | |
| SCHEMBL10433173 | 0.76 | KDM4E (0.54) | KDM4ECA12CA9MAPTMAPK1 | |
| SCHEMBL10886255 | 0.76 | KDM4E (0.46) | KDM4ECA12CA9MAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983756-A | DIAGNOSING LIVER, KIDNEY DISORDERS | NITTO BOSEKI CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |