Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CFD | P00746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28662068 | 0.86 | HSD17B10 (0.65) | KDM4EHSD17B10ACHEMAPTMAPK1 | |
| SCHEMBL27594594 | 0.85 | KDM4E (0.64) | KDM4EHSD17B10ACHEMAPTMAPK1 | |
| SCHEMBL4360840 | 0.85 | KDM4E (0.73) | KDM4EHSD17B10ACHEMAPTMAPK1 | |
| SCHEMBL7325805 | 0.84 | KDM4E (0.53) | KDM4EHSD17B10ACHEMAPTMAPK1 | |
| SCHEMBL2425701 | 0.84 | KMT2A (0.50) | KDM4EALDH1A1TDP1HTT | |
| SCHEMBL7326050 | 0.84 | KDM4E (0.53) | KDM4EHSD17B10ACHEMAPTMAPK1 | |
| SCHEMBL8416646 | 0.83 | ELANE (0.54) | KDM4EHSD17B10ACHEMAPTMAPK1 | |
| SCHEMBL7623240 | 0.82 | POLB (0.54) | KDM4EMAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL23540433 | 0.82 | KDM4E (0.51) | KDM4EHSD17B10ACHEMAPTMAPK1 | |
| SCHEMBL5121870 | 0.81 | ALDH1A1 (0.73) | KDM4EHSD17B10MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103930409-B | Armaticity amide thiazole, containing its cosmetic or dermatological preparations and their purposes overcoming and preventing less desirable cutaneous pigmentation | 拜尔斯道夫股份公司 | 2016-08-24 | — | — | CN | disclosed |
| EP-1238961-B1 | Process for the preparation of benzyl esters of hydroxybenzoic acids | BAYER CHEMICALS AG (DE) | 2005-01-26 | — | — | EP | disclosed |
| US-6600064-B2 | Reacting dibenzyl ethers with alkylcarbonyloxybenzoic or alkoxycarbonyloxybenzoic acids in the presence of one or more acids as catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-29 | — | — | US | disclosed |
| US-20020128523-A1 | Process for the preparation of hydroxybenzoic benzyl esters | LANXESS DEUTSCHLAND GMBH (DE) | 2002-09-12 | — | — | US | disclosed |
| EP-1238961-A1 | Process for the preparation of benzyl esters of hydroxybenzoic acids | Bayer Aktiengesellschaft (DE) | 2002-09-11 | — | — | EP | disclosed |
| US-RE32196-E | PROPHYLACTIC CHEMOTHERAPY OF ALLERGIC CONDITIONS | LILLY INDUSTRIES LIMITED (GB) | 1986-07-01 | — | — | US | disclosed |
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |
| EP-0026609-B1 | AROMATIC POLYESTER AND FILAMENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4259340-A | PROPHYLACTIC CHEMOTHERAPY OF ALLERGIC CONDITIONS SUCH AS ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128523-A1 | Process for the preparation of hydroxybenzoic benzyl esters | HAAO, HPD, ALKBH3 | KDM4E 202/4885HSD17B10 16/4885ACHE 2917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.