Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.48 |
| ▸ | CMA1 | P23946 | 2/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 3/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.40 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31010750 | 0.87 | AHR (0.59) | AHRCMA1PDE3BPDE3AEIF2AK2 | |
| SCHEMBL9834566 | 0.75 | AHR (0.44) | AHRCMA1PDE3BPDE3AEIF2AK2 | |
| SCHEMBL548762 | 0.72 | AHR (0.50) | AHRCMA1PDE3BPDE3AEIF2AK2 | |
| SCHEMBL1436084 | 0.72 | GRIA1 (0.53) | AHRCMA1PDE3BPDE3AEIF2AK2 | |
| SCHEMBL5441646 | 0.72 | AHR (0.60) | AHRCMA1PDE3BPDE3AEIF2AK2 | |
| SCHEMBL4065845 | 0.72 | AHR (0.60) | AHRCMA1PDE3BPDE3AEIF2AK2 | |
| SCHEMBL9298074 | 0.72 | AHR (0.50) | AHRCMA1PDE3BPDE3AEIF2AK2 | |
| SCHEMBL2491904 | 0.72 | AHR (0.50) | AHRCMA1PDE3BPDE3AEIF2AK2 | |
| SCHEMBL578508 | 0.72 | SRC (0.57) | AHRCMA1PDE3BPDE3AEIF2AK2 | |
| SCHEMBL18388811 | 0.71 | HDAC1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981864-A | ANTICOAGULANTS | BOEHRINGER MANNEHIM GMBH (DE) | 1991-01-01 | — | — | US | disclosed |