Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326099 | 0.77 | CYP4F2 (0.44) | NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL7594644 | 0.76 | TDP1 (0.44) | NR1H2NR1H3 | |
| SCHEMBL10977227 | 0.75 | CYP4F2 (0.41) | MTNR1AMTNR1BNR1H2NR1H3 | |
| SCHEMBL13269643 | 0.74 | DAO (0.53) | STING1FFAR1DAO | |
| SCHEMBL13141316 | 0.72 | MAPT (0.40) | AOC3DAO | |
| SCHEMBL10982252 | 0.71 | CYP4F2 (0.50) | MTNR1AMTNR1BNR1H2NR1H3FFAR1 | |
| SCHEMBL9762994 | 0.71 | APP (0.40) | — | |
| SCHEMBL7322522 | 0.71 | CYP4F2 (0.44) | NR1H2NR1H3 | |
| SCHEMBL15608606 | 0.71 | CYP4F2 (0.44) | MTNR1AMTNR1BNR1H2NR1H3 | |
| SCHEMBL38658706 | 0.71 | MTNR1A (0.39) | STING1HDAC8MTNR1AMTNR1BMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034381-A | Antagonist | CIBA-GEIGY CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |
| EP-0323807-A2 | Certain 2-substituted adenosine derivatives | CIBA-GEIGY AG (CH) | 1989-07-12 | — | — | EP | disclosed |