Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11179784 | 1.00 | TSHR (0.46) | TSHRSMN1; SMN2SPHK1MAPTTRPA1 | |
| SCHEMBL1786274 | 0.93 | SPHK1 (0.52) | TSHRSMN1; SMN2SPHK1MAPTTRPA1 | |
| SCHEMBL1781451 | 0.91 | SPHK1 (0.55) | SPHK1MAPTTRPA1DDAH1GAPDH | |
| SCHEMBL1783266 | 0.91 | SPHK1 (0.55) | SPHK1MAPTTRPA1DDAH1GAPDH | |
| SCHEMBL5499873 | 0.86 | — | — | |
| SCHEMBL1782596 | 0.86 | — | — | |
| SCHEMBL1784185 | 0.84 | TSHR (0.41) | TSHRSMN1; SMN2SPHK1MAPTTRPA1 | |
| SCHEMBL27279991 | 0.83 | ALDH1A1 (0.45) | TSHRSPHK1CYP2D6ADH1BADH1C | |
| SCHEMBL1783970 | 0.82 | LMNA (0.39) | SPHK1TRPA1LMNABLMCYP3A4 | |
| SCHEMBL1784709 | 0.82 | TRPA1 (0.39) | SPHK1MAPTTRPA1DDAH1GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| EP-0043462-B1 | ALKOXYALKYL-AMINOTRIAZINE-TRANSETHERIFYING PRODUCTS AND THEIR USE | BASF Aktiengesellschaft (DE) | 1985-05-08 | — | — | EP | disclosed |
| EP-0075822-B1 | PROCESS FOR THE PREPARATION OF AMINOPLAST RESINS AND THEIR USE | BASF Aktiengesellschaft (DE) | 1985-04-24 | — | — | EP | disclosed |
| US-4393207-A | BAKING FINISHES, ACID-HARDENING COATINGS | BASF AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| US-4387212-A | AMINOTRIAZINE, HYDROXYALDEHYDE | BASF AKTIENGESELLSCHAFT (DE) | 1983-06-07 | — | — | US | disclosed |
| EP-0075822-A1 | Process for the preparation of aminoplast resins and their use | BASF Aktiengesellschaft (DE) | 1983-04-06 | — | — | EP | disclosed |
| EP-0043462-A2 | Alkoxyalkyl-aminotriazine-transetherifying products and their use | BASF Aktiengesellschaft (DE) | 1982-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | TSHR 2479/4885SMN1; SMN2 2144/4885SPHK1 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.