SCHEMBL9763218

SCHEMBL9763218

COCCN(CCOC)c1ccccc1OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA12 O43570 1/20 0.44
CA4 P22748 1/20 0.44
CA14 Q9ULX7 1/20 0.44
HTR7 P34969 1/20 0.42
ALDH1A1 P00352 2/20 0.40
AOC3 Q16853 1/20 0.40
ESR1 P03372 1/20 0.39
CRHR1 P34998 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
TP53 P04637 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TSHR P16473 1/20 0.38
ADRA2B P18089 1/20 0.38
PTGS1 P23219 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9763237 0.84 ALDH1A1 (0.43) ALDH1A1TDP1
SCHEMBL10690592 0.82 CA12 (0.46) CA1CA2CA7CA9CA12
SCHEMBL11808509 0.81 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL5470095 0.81 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL3779042 0.81 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL1573613 0.79 CYP1A2 (0.47) CA1CA2CA7CA9CA12
Hydrochloric Acid SCHEMBL11504948 0.79 CA1 (0.43) CA1CA2CA7CA9CA12
Bromide SCHEMBL11808501 0.79 CA1 (0.43) CA1CA2CA7CA9CA12
SCHEMBL11133752 0.78 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL9424150 0.77 KMT2A (0.38) CA2ALDH1A1CRHR1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4997918-A Benzthiazolium azo dyes CIBA-GEIGY CORPORATION (US) 1991-03-05 US disclosed
EP-0105031-B1 CATIONIC AZO DYESTUFFS CIBA-GEIGY AG (CH) 1989-01-04 EP disclosed
EP-0105031-A2 Cationic azo dyestuffs CIBA-GEIGY AG (CH) 1984-04-04 EP disclosed