Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763680 | 0.87 | TDP1 (0.42) | TDP1L3MBTL1FFAR1IDO1NAAA | |
| SCHEMBL9763645 | 0.83 | TDP1 (0.44) | TDP1L3MBTL1FFAR1IDO1NAAA | |
| SCHEMBL9763493 | 0.81 | TDP1 (0.46) | TDP1L3MBTL1FFAR1IDO1NAAA | |
| SCHEMBL9574201 | 0.80 | TDP1 (0.41) | TDP1L3MBTL1FFAR1IDO1NAAA | |
| SCHEMBL9574219 | 0.80 | TDP1 (0.41) | TDP1L3MBTL1FFAR1IDO1NAAA | |
| SCHEMBL9670853 | 0.78 | TDP1 (0.51) | TDP1L3MBTL1FFAR1IDO1LMNA | |
| SCHEMBL9763611 | 0.78 | ALDH1A1 (0.49) | FFAR1MAPTRXFP1 | |
| SCHEMBL198056 | 0.78 | IDO1 (0.58) | TDP1L3MBTL1IDO1MAOAMEN1 | |
| SCHEMBL9574242 | 0.77 | TDP1 (0.47) | TDP1L3MBTL1FFAR1IDO1NAAA | |
| SCHEMBL2010505 | 0.77 | TDP1 (0.52) | TDP1L3MBTL1FFAR1IDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |