Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763028 | 0.74 | — | — | |
| SCHEMBL9254155 | 0.67 | LMNA (0.38) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL1133347 | 0.64 | — | — | |
| SCHEMBL229792 | 0.62 | TSHR (0.50) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL72471 | 0.62 | LMNA (0.62) | LMNATSHRALDH1A1 | |
| SCHEMBL6241297 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL6787736 | 0.62 | LMNA (0.45) | LMNATSHRKDM4EALDH1A1 | |
| Bromide SCHEMBL17768385 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL1133346 | 0.62 | — | — | |
| Ammonia Solution, Strong SCHEMBL27485718 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026862-A | Process for the preparation of 1.R, cis cyclopropane di-carboxylic acid derivatives | ROUSSEL UCLAF (FR) | 1991-06-25 | — | — | US | disclosed |
| EP-0094304-B1 | PROCESS FOR THE PREPARATION OF CYCLOPROPANECARBOXYLIC-ACID DERIVATIVES, AND INTERMEDIATES THEREFOR | ROUSSEL-UCLAF (FR) | 1986-03-12 | — | — | EP | disclosed |
| EP-0094304-A1 | Process for the preparation of cyclopropanecarboxylic-acid derivatives, and intermediates therefor | ROUSSEL-UCLAF (FR) | 1983-11-16 | — | — | EP | disclosed |