Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763371 | 1.00 | FDPS (0.48) | FDPSAPPTUBB1POLBNFE2L2 | |
| SCHEMBL2684387 | 0.88 | CYP1A1 (0.57) | APPTUBB1NFE2L2CYP1A1PTGS1 | |
| SCHEMBL4092723 | 0.88 | CYP1A1 (0.57) | APPTUBB1NFE2L2CYP1A1PTGS1 | |
| SCHEMBL4686225 | 0.82 | TUBB1 (0.56) | TUBB1NFE2L2CYP1A1PTGS1PTGS2 | |
| SCHEMBL4686223 | 0.82 | TUBB1 (0.56) | TUBB1NFE2L2CYP1A1PTGS1PTGS2 | |
| SCHEMBL10463991 | 0.81 | APP (0.63) | APPKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10463994 | 0.81 | APP (0.63) | APPKDM4EALDH1A1HPGDSMN1; SMN2 | |
| Acetic Acid SCHEMBL8820510 | 0.81 | SMN1; SMN2 (0.59) | FDPSAPPPOLBNFE2L2CYP1A1 | |
| SCHEMBL13572437 | 0.79 | FDPS (0.50) | FDPSTUBB1POLBNFE2L2CYP1A1 | |
| SCHEMBL4264179 | 0.78 | FDPS (0.49) | FDPSAPPTUBB1POLBNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |
| US-4853382-A | TREATING ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0178919-B1 | AMINOPHENOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4730008-A | STIMULANT FOR BETA-ADRENORECEPTORS | GLAXO GROUP LIMITED (GB) | 1988-03-08 | — | — | US | disclosed |
| EP-0178919-A2 | Aminophenol derivatives | GLAXO GROUP LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |