Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19883160 | 1.00 | KMT2A (0.43) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL2741529 | 0.95 | KMT2A (0.40) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL9764354 | 0.92 | HTT (0.37) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL13671356 | 0.92 | KMT2A (0.37) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL8005484 | 0.86 | SCN9A (0.36) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL20276018 | 0.86 | KMT2A (0.42) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL20152470 | 0.86 | KMT2A (0.42) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL14281230 | 0.85 | KMT2A (0.41) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL14408319 | 0.85 | KMT2A (0.41) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL12718792 | 0.85 | TDP1 (0.39) | KMT2AHTTSMN1; SMN2TDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |