Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004608 | 0.91 | CA2 (0.35) | SCN9AGPR119HCRTR2F2CA2 | |
| SCHEMBL8018365 | 0.89 | SCN9A (0.34) | SCN9AGPR119HCRTR2F2CA2 | |
| SCHEMBL8018364 | 0.89 | SCN9A (0.34) | SCN9AGPR119HCRTR2F2CA2 | |
| SCHEMBL8020228 | 0.88 | GPR119 (0.34) | SCN9AGPR119HCRTR2F2CA2 | |
| SCHEMBL8018612 | 0.88 | GPR119 (0.34) | SCN9AGPR119HCRTR2F2CA2 | |
| SCHEMBL8021671 | 0.87 | GPR119 (0.34) | SCN9AGPR119HCRTR2F2CA2 | |
| SCHEMBL8016132 | 0.87 | GPR119 (0.34) | SCN9AGPR119HCRTR2F2CA2 | |
| SCHEMBL8016127 | 0.87 | GPR119 (0.34) | SCN9AGPR119HCRTR2F2CA2 | |
| SCHEMBL8016126 | 0.87 | GPR119 (0.34) | SCN9AGPR119HCRTR2F2CA2 | |
| SCHEMBL8014473 | 0.86 | MAPT (0.39) | SCN9AGPR119CA2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6149990-A | Carboxylate derivatives comprising an ether group and liquid crystal composition comprising the same | CHISSO CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0884302-A1 | CARBOXYLIC ESTER DERIVATIVES CONTAINING ETHER GROUP AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1998-12-16 | — | — | EP | disclosed |