Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763882 | 0.78 | HMGCR (0.51) | HMGCR | |
| SCHEMBL9763471 | 0.77 | HMGCR (0.50) | HMGCR | |
| SCHEMBL9763466 | 0.77 | HMGCR (0.50) | HMGCR | |
| SCHEMBL3817255 | 0.75 | HMGCR (0.49) | HMGCR | |
| SCHEMBL9763456 | 0.75 | KDM4E (0.44) | — | |
| SCHEMBL9724600 | 0.74 | HMGCR (0.53) | HMGCR | |
| SCHEMBL9763534 | 0.73 | KDM4E (0.42) | — | |
| SCHEMBL3819551 | 0.72 | HMGCR (0.45) | HMGCR | |
| SCHEMBL13717261 | 0.72 | HMGCR (0.45) | HMGCR | |
| SCHEMBL9730278 | 0.71 | HMGCR (0.46) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004747-A | Isoquinolinones | MAY & BAKER LIMITED (GB) | 1991-04-02 | — | — | US | disclosed |