Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119640 | 0.87 | TDP1 (0.44) | HRH3TDP1SIRT2SIRT1HCAR3 | |
| Water SCHEMBL30938808 | 0.85 | TDP1 (0.43) | HRH3TDP1SIRT2SIRT1HCAR3 | |
| SCHEMBL8424370 | 0.85 | TDP1 (0.43) | HRH3TDP1SIRT2SIRT1HCAR3 | |
| Ammonia Solution, Strong SCHEMBL6052079 | 0.85 | TDP1 (0.43) | HRH3TDP1SIRT2SIRT1HCAR3 | |
| SCHEMBL10347628 | 0.84 | TDP1 (0.42) | HRH3TDP1SIRT2SIRT1HCAR3 | |
| Benzotriazole SCHEMBL27645577 | 0.81 | MGAM (0.37) | TDP1ALOX15TSHRKDM4EALDH1A1 | |
| Ethylene Glycol SCHEMBL4618490 | 0.81 | NPSR1 (0.43) | HRH3TDP1SIRT2SIRT1HCAR3 | |
| Ethylene Glycol SCHEMBL4617853 | 0.81 | NPSR1 (0.43) | HRH3TDP1SIRT2SIRT1HCAR3 | |
| Trifluoroacetic Acid SCHEMBL27736713 | 0.78 | SMN1; SMN2 (0.44) | HRH3TDP1SIRT2SIRT1HCAR3 | |
| SCHEMBL52479 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247549-B1 | PHOTOPOLYMERIZABLE COMPOSITION CONTAINING CARBOXY BENZOTRIAZOLE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-11-27 | — | — | EP | claimed |