Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25443654 | 0.79 | MAOA (0.42) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6724547 | 0.78 | TSHR (0.55) | TSHRKMT2AMEN1NPC1MAPT | |
| SCHEMBL11271367 | 0.78 | TSHR (0.55) | TSHRKMT2AMEN1NPC1MAPT | |
| SCHEMBL755941 | 0.77 | TSHR (0.59) | TSHRKMT2AMEN1NPC1MAPT | |
| SCHEMBL27999815 | 0.76 | TSHR (0.53) | TSHRKMT2AMEN1NPC1MAPT | |
| SCHEMBL9225409 | 0.76 | TSHR (0.57) | TSHRKMT2AMEN1NPC1MAPT | |
| Trimethylammonium SCHEMBL27818073 | 0.76 | TSHR (0.57) | TSHRKMT2AMEN1NPC1MAPT | |
| SCHEMBL12158744 | 0.76 | TSHR (0.57) | TSHRKMT2AMEN1NPC1MAPT | |
| SCHEMBL11768086 | 0.76 | TSHR (0.57) | TSHRKMT2AMEN1NPC1MAPT | |
| Hydrochloric Acid SCHEMBL29091991 | 0.76 | TSHR (0.57) | TSHRKMT2AMEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068368-A | Reaction of lithium amide with acetylene and reaction with a ketone | CYPRUS FOOTE MINERAL COMPANY (US) | 1991-11-26 | — | — | US | disclosed |