SCHEMBL9763719

SCHEMBL9763719

Cc1cc(O)ccc1C(C)c1ccc(O)cc1C

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 7/20 0.47
ESR1 P03372 6/20 0.47
TYR P14679 1/20 0.47
CHRM1 P11229 2/20 0.42
ADRA1A P35348 2/20 0.42
HTR2B P41595 2/20 0.42
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
MAOA P21397 1/20 0.42
TBXA2R P21731 1/20 0.42
ACHE P22303 1/20 0.40
TRPA1 O75762 1/20 0.40
LMNA P02545 1/20 0.40
SLC6A2 P23975 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12324037 0.92 TYR (0.59) ESR2ESR1TYRCHRM1ADRA1A
SCHEMBL8385836 0.86 ESR2 (0.47) ESR2ESR1TYRCHRM1ADRA1A
SCHEMBL29366027 0.86 HTR2B (0.50) ESR2ESR1TYRCHRM1ADRA1A
SCHEMBL133674 0.86 HTR2B (0.50) ESR2ESR1TYRCHRM1ADRA1A
SCHEMBL12323453 0.84 TYR (0.71) ESR2ESR1TYRADRA1AHTR2B
Hydrochloric Acid SCHEMBL7078662 0.84 HTR2B (0.48) ESR2ESR1TYRCHRM1ADRA1A
SCHEMBL27564626 0.84 HTR2B (0.48) ESR2ESR1TYRCHRM1ADRA1A
SCHEMBL2501926 0.83 ESR2 (0.49) ESR2ESR1TYRCHRM1ADRA1A
SCHEMBL29465793 0.83 ESR2 (0.49) ESR2ESR1TYRCHRM1ADRA1A
Hydrochloric Acid SCHEMBL6039804 0.82 LMNA (0.47) ESR2ESR1TYRCHRM1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011116050-A2 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2011-09-22 WO disclosed
US-5021528-A Crosslinked bisphenol containing arylcyclobutene alkyl ethers and cured compositions therefrom SHELL OIL COMPANY (US) 1991-06-04 US disclosed
US-4943665-A Modified bisphenols containing arylcyclobutenealkyl ethers and cured compositions therefrom SHELL OIL COMPANY (US) 1990-07-24 US disclosed