Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763859 | 1.00 | NFE2L2 (0.40) | NFE2L2LTB4R2KEAP1RARBRARA | |
| SCHEMBL9764278 | 0.97 | NFE2L2 (0.41) | NFE2L2LTB4R2KEAP1RARBRARA | |
| SCHEMBL9764275 | 0.97 | NFE2L2 (0.41) | NFE2L2LTB4R2KEAP1RARBRARA | |
| SCHEMBL9764355 | 0.96 | NFE2L2 (0.40) | NFE2L2LTB4R2KEAP1RARBRARA | |
| SCHEMBL9763643 | 0.96 | NFE2L2 (0.40) | NFE2L2LTB4R2KEAP1RARBRARA | |
| SCHEMBL9763570 | 0.96 | NFE2L2 (0.40) | NFE2L2LTB4R2KEAP1RARBRARA | |
| SCHEMBL9763638 | 0.96 | NFE2L2 (0.40) | NFE2L2LTB4R2KEAP1RARBRARA | |
| SCHEMBL9763995 | 0.96 | NFE2L2 (0.40) | NFE2L2LTB4R2KEAP1RARBRARA | |
| SCHEMBL9764351 | 0.96 | NFE2L2 (0.40) | NFE2L2LTB4R2KEAP1RARBRARA | |
| SCHEMBL9763976 | 0.96 | NFE2L2 (0.40) | NFE2L2LTB4R2KEAP1RARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |