Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712540 | 0.80 | LMNA (0.48) | NPC1RAB9ASMN1; SMN2PKMMITF | |
| SCHEMBL29145521 | 0.75 | KDM4E (0.45) | RAB9ASMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL1291219 | 0.74 | ELANE (0.44) | ALDH1A1KDM4ELMNAHPGDESR1 | |
| SCHEMBL29145515 | 0.74 | PLCG1 (0.44) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL9671426 | 0.72 | KMT2A (0.43) | NPC1RAB9ASMN1; SMN2PKMMITF | |
| SCHEMBL28896336 | 0.71 | KDM4E (0.43) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL27712539 | 0.69 | LMNA (0.51) | NPC1RAB9ASMN1; SMN2PKMMITF | |
| SCHEMBL29145518 | 0.69 | SSTR4 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL15303617 | 0.68 | KDM4E (0.50) | ALDH1A1KDM4EHPGD | |
| SCHEMBL3432978 | 0.67 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047521-A | Anticarcinogenic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |