Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416096 | 0.84 | CYP3A4 (0.42) | CYP3A4TSHR | |
| SCHEMBL3836353 | 0.81 | TSHR (0.53) | CYP3A4GABRA1GABRB2NOS3NOS1 | |
| SCHEMBL9623463 | 0.81 | GABRA1 (0.47) | CYP3A4GABRA1GABRB2NOS3NOS1 | |
| SCHEMBL1594654 | 0.79 | CYP3A4 (0.47) | CYP3A4GABRA1GABRB2TSHRTRPA1 | |
| SCHEMBL462794 | 0.77 | CYP3A4 (0.52) | CYP3A4GABRA1GABRB2NOS3NOS1 | |
| SCHEMBL28864346 | 0.77 | CYP3A4 (0.52) | CYP3A4GABRA1GABRB2NOS3NOS1 | |
| SCHEMBL29795971 | 0.75 | GABRA1 (0.61) | CYP3A4GABRA1GABRB2NOS3NOS1 | |
| SCHEMBL93290 | 0.75 | GABRA1 (0.61) | CYP3A4GABRA1GABRB2NOS3NOS1 | |
| SCHEMBL7562170 | 0.73 | CYP3A4 (0.44) | CYP3A4GABRA1GABRB2NOS3NOS1 | |
| SCHEMBL4235215 | 0.73 | CYP3A4 (0.47) | CYP3A4GABRA1GABRB2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4747953-A | Composite membranes based on interpenetrating polymer networks | ALLIED CORPORATION (US) | 1988-05-31 | — | — | US | claimed |
| US-4695483-A | Method for the preparation of composite membranes based on interpenetrating polymer networks | ALLIED CORPORATION (US) | 1987-09-22 | — | — | US | claimed |
| US-4613440-A | ISOCYANTE-CAPPED POLYETHER, POLYVINYL PYRIDINE OR PYRROLIDONE, POLYUREA, SEMIPERMEABILITY | ALLIED CORPORATION (US) | 1986-09-23 | — | — | US | claimed |
| EP-3838892-B1 | METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2022-10-12 | — | — | EP | disclosed |
| EP-3293173-B1 | METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2021-07-28 | — | — | EP | disclosed |
| EP-3838892-A1 | METHOD FOR PRODUCING ISOCYANATE | Asahi Kasei Kabushiki Kaisha (JP) | 2021-06-23 | — | — | EP | disclosed |
| EP-2980066-B1 | METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2021-04-21 | — | — | EP | disclosed |
| EP-3293173-A1 | METHOD FOR PRODUCING ISOCYANATE | Asahi Kasei Kabushiki Kaisha (JP) | 2018-03-14 | — | — | EP | disclosed |
| US-9714215-B2 | Method for producing isocyanate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2017-07-25 | — | — | US | disclosed |
| US-20160052874-A1 | METHOD FOR PRODUCING ISOCYANATE | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-02-25 | — | — | US | disclosed |
| EP-2980066-A1 | METHOD FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2016-02-03 | — | — | EP | disclosed |
| US-5018380-A | Organometallic gas carrier in interpenetrating polymer network | ALLIED-SIGNAL INC. (US) | 1991-05-28 | — | — | US | disclosed |
| US-4747953-A | Composite membranes based on interpenetrating polymer networks | ALLIED CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |
| US-4695483-A | Method for the preparation of composite membranes based on interpenetrating polymer networks | ALLIED CORPORATION (US) | 1987-09-22 | — | — | US | disclosed |
| US-4627859-A | ORGANOMETALLIC GAS CARRIER INTERDISPERSED IN INTERPENE TRATING POLYMER NETWORK MATRIX | ALLIED CORPORATION (US) | 1986-12-09 | — | — | US | disclosed |
| US-4613440-A | ISOCYANTE-CAPPED POLYETHER, POLYVINYL PYRIDINE OR PYRROLIDONE, POLYUREA, SEMIPERMEABILITY | ALLIED CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160052874-A1 | METHOD FOR PRODUCING ISOCYANATE | CPS1, ALKBH3, IDH3A | CYP3A4 229/4885GABRA1 4344/4885GABRB2 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.