⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1407016 | 0.62 | — | — | |
| SCHEMBL7359836 | 0.61 | — | — | |
| SCHEMBL28325898 | 0.60 | — | — | |
| SCHEMBL27497716 | 0.60 | — | — | |
| SCHEMBL12496409 | 0.56 | — | — | |
| SCHEMBL12601101 | 0.56 | RAB9A (0.32) | — | |
| SCHEMBL9697351 | 0.55 | POLB (0.32) | — | |
| SCHEMBL10640679 | 0.53 | — | — | |
| SCHEMBL21237406 | 0.53 | CHRM2 (0.32) | — | |
| SCHEMBL25718283 | 0.52 | CHRM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255307-B1 | PROCESS FOR THE SYNTHESIS OF PENEMS | PFIZER INC. (US) | 1991-12-04 | — | — | EP | disclosed |
| EP-0320497-A1 | Substituted 2-thioxopenams, intermediates therefrom and process for preparing substituted 2-thioxopenams and 2-substituted thiopenems | MERCK & CO. INC. (US) | 1989-06-14 | — | — | EP | disclosed |