Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880352 | 0.78 | SMN1; SMN2 (0.58) | TP53HBBSMN1; SMN2DHFRALDH1A1 | |
| SCHEMBL464610 | 0.78 | SMN1; SMN2 (0.58) | TP53HBBSMN1; SMN2DHFRALDH1A1 | |
| SCHEMBL11360323 | 0.73 | TP53 (0.57) | TP53HBBSMN1; SMN2DHFR | |
| SCHEMBL10806648 | 0.71 | SMN1; SMN2 (0.54) | TP53HBBSMN1; SMN2DHFRALDH1A1 | |
| SCHEMBL10521423 | 0.71 | DAO (0.34) | DAO | |
| SCHEMBL1715101 | 0.70 | TP53 (0.48) | TP53HBBSMN1; SMN2DHFRALDH1A1 | |
| Teroxirone SCHEMBL10993252 | 0.69 | TP53 (0.78) | TP53HBBSMN1; SMN2DHFRALDH1A1 | |
| Teroxirone SCHEMBL11263571 | 0.69 | TP53 (0.78) | TP53HBBSMN1; SMN2DHFRALDH1A1 | |
| SCHEMBL779781 | 0.69 | SMN1; SMN2 (0.71) | TP53HBBSMN1; SMN2DHFRALDH1A1 | |
| SCHEMBL21119006 | 0.69 | TP53 (0.64) | TP53HBBSMN1; SMN2DHFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801601-A | ANTILEUKEMIA AGENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-01-31 | — | — | US | claimed |
| US-4740527-A | REACTION PRODUCT OF POLYISOCYANATES AND REACTIVE COMPOUNDS IN PRESENCE OF POLYEPOXIDES; CARBONIZATION AUXILIARIES; FILLERS; FIREPROOFING | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | claimed |
| EP-0093959-B1 | PROCESS FOR THE PREPARATION OF GLYCIDYL-1,2,4-TRIAZOLIDIN-3,5-DIONES | BAYER AG (DE) | 1987-03-04 | — | — | EP | claimed |
| EP-0056962-B1 | N-SUBSTITUTED POLYGLYCIDYL URAZOL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Henkel Kommanditgesellschaft auf Aktien (DE) | 1985-10-02 | — | — | EP | claimed |
| US-4467099-A | REACTION OF TRIAZOLIDINES WITH EPIHALOHYDRINS | BAYER AKTIENGESELLSCHAFT (DE) | 1984-08-21 | — | — | US | claimed |
| EP-0044422-B1 | GLYCIDYL-1,2,4-TRIAZOLIDINE-3,5 DIONES AND A METHOD FOR THEIR PREPARATION | BAYER AG (DE) | 1983-10-19 | — | — | EP | claimed |
| EP-0044422-A1 | Glycidyl-1,2,4-triazolidine-3,5 diones and a method for their preparation | BAYER AG (DE) | 1982-01-27 | — | — | EP | claimed |
| JP-58206587-A | — | — | None | — | — | JP | disclosed |
| JP-57045183-A | — | — | None | — | — | JP | disclosed |
| CN-107532424-A | Reinforcing rod, manufacture method and purposes | 赢创德固赛有限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107011628-A | For the composition epoxy resin for the composite for preparing stable storing | 赢创德固赛有限公司 | 2017-08-04 | — | — | CN | disclosed |
| EP-0262527-B1 | OPTIONALLY CELLULAR POLYURETHANES JOINED TO OR MANUFACTURED WITH ANOTHER MATERIAL, AND A PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1991-12-04 | — | — | EP | disclosed |
| EP-0224138-B1 | POSSIBLY POROUS INTUMESCENT MASSES | BAYER AG (DE) | 1991-05-29 | — | — | EP | disclosed |
| EP-0044422-B1 | GLYCIDYL-1,2,4-TRIAZOLIDINE-3,5 DIONES AND A METHOD FOR THEIR PREPARATION | BAYER AG (DE) | 1983-10-19 | — | — | EP | disclosed |
| EP-0044422-B1 | GLYCIDYL-1,2,4-TRIAZOLIDINE-3,5 DIONES AND A METHOD FOR THEIR PREPARATION | BAYER AG (DE) | 1983-10-19 | — | — | EP | disclosed |
| EP-0056962-A2 | N-substituted polyglycidyl urazol compounds, process for their preparation and pharmaceutical compositions containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1982-08-04 | — | — | EP | disclosed |
| JP-S5745183-A | NOVEL GLYCIDYL-1,2,4-TRIAZOLIDINE-3,5-DIONES | BAYER AG | 1982-03-13 | — | — | JP | disclosed |
| EP-0044422-A1 | Glycidyl-1,2,4-triazolidine-3,5 diones and a method for their preparation | BAYER AG (DE) | 1982-01-27 | — | — | EP | disclosed |
| EP-0044422-A1 | Glycidyl-1,2,4-triazolidine-3,5 diones and a method for their preparation | BAYER AG (DE) | 1982-01-27 | — | — | EP | disclosed |
| EP-0044422-A1 | Glycidyl-1,2,4-triazolidine-3,5 diones and a method for their preparation | BAYER AG (DE) | 1982-01-27 | — | — | EP | disclosed |