SCHEMBL464610

SCHEMBL464610

O=c1[nH]c(=O)n(CC2CO2)c(=O)[nH]1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.58
TP53 P04637 1/20 0.58
HBB P68871 1/20 0.58
DHFR P00374 1/20 0.42
MAPT P10636 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 1/20 0.31
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16880352 1.00 SMN1; SMN2 (0.58) SMN1; SMN2TP53HBBDHFRMAPT
SCHEMBL1715101 0.91 TP53 (0.48) SMN1; SMN2TP53HBBDHFRMAPT
SCHEMBL2340342 0.88 TP53 (0.46) SMN1; SMN2TP53HBBDHFRALDH1A1
SCHEMBL1715736 0.86 TP53 (0.44) SMN1; SMN2TP53HBBDHFRALDH1A1
Tromethamine SCHEMBL21799163 0.85 TP53 (0.43) SMN1; SMN2TP53HBBDHFRMEN1
SCHEMBL1714962 0.85 ALDH1A1 (0.46) SMN1; SMN2TP53HBBDHFRMAPT
Acrylic Acid SCHEMBL28073530 0.85 TP53 (0.43) SMN1; SMN2TP53HBBDHFR
SCHEMBL123343 0.83 TP53 (0.42) SMN1; SMN2TP53HBBDHFR
SCHEMBL5070119 0.83 ALDH1A1 (0.53) SMN1; SMN2TP53HBBALDH1A1
SCHEMBL779781 0.83 SMN1; SMN2 (0.71) SMN1; SMN2TP53HBBDHFRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137851-A1 FIBROUS AMINE-FUNCTIONALIZED MATRIX (FAM) FOR CONTAMINANT REMOVAL FROM GASEOUS AND LIQUID SOURCES, METHODS OF MAKING AND USE BATTELLE MEMORIAL INSTITUTE (US) 2024-06-27 WO claimed
CN-117003933-B Soap-free polymeric cationic dispersion and preparation method thereof 江门市金桥新材料有限公司 2024-01-19 CN claimed
CN-117003933-A Soap-free polymeric cationic dispersion and preparation method thereof 江门市金桥新材料有限公司 2023-11-07 CN claimed
WO-2023146300-A1 E-STONE BASED ARTIFICIAL MARBLE AND MANUFACTURING METHOD THEREFOR (주)엘엑스하우시스 2023-08-03 WO claimed
CN-115975554-A Acrylate pressure-sensitive adhesive, and preparation method and application thereof 四川普利司德高分子新材料有限公司 2023-04-18 CN claimed
CN-111875778-B Method for preparing epoxy resin from triglycidyl isocyanurate production by-product 江苏扬农化工集团有限公司 2022-12-09 CN claimed
CN-115232446-A High-temperature-resistant plastic powder for kitchen appliances and production process thereof 绍兴市英纳粉末涂料有限公司 2022-10-25 CN claimed
CN-108884082-B Monoglycidyl isocyanurate compound and method for producing same 日产化学株式会社 2022-09-20 CN claimed
CN-109073561-B Detection of organic chemicals 梁庆耀 2022-06-03 CN claimed
CN-114206902-A Method for modifying a peptide immobilized on a solid support by means of a traceless reductively cleavable linker molecule 贝兰迪克有限责任公司 2022-03-18 CN claimed
EP-0132746-B1 PROCESS FOR THE PRODUCTION OF ELECTRICALLY INSULATING COMPOSITES SIEMENS AKTIENGESELLSCHAFT (DE) 1986-10-15 EP claimed
EP-0044872-B1 PROCESS FOR SELECTIVELY SEPARATING WATER-SOLUBLE VALUABLE MATERIALS FROM AN AQUEOUS SOLUTION CONTAINING SAME TORAY INDUSTRIES, INC. (JP) 1985-09-18 EP claimed
US-4529779-A From aromatic dicarboxylic acid and glycol; reducing carboxyl end groups UNITIKA LIMITED (JP) 1985-07-16 US claimed
EP-0132746-A1 Process for the production of electrically insulating composites SIEMENS AKTIENGESELLSCHAFT (DE) 1985-02-13 EP claimed
US-4390664-A A CURABLE GLYCIDYL ETHER OF A PHENOL-ALDEHYDE TYPE ADDUCT MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1983-06-28 US claimed
US-4369207-A PHOTOPOLYMERIZING TEIJIN LIMITED (JP) 1983-01-18 US claimed
EP-0044872-A1 PROCESS FOR SELECTIVELY SEPARATING WATER-SOLUBLE VALUABLE MATERIALS FROM AN AQUEOUS SOLUTION CONTAINING SAME TORAY INDUSTRIES, INC. (JP) 1982-02-03 EP claimed
US-4292151-A MELT SPINNING THE BLOCK POLYMER WITH AN UNSATURATED COMPOUND; CURING WITH ACTINIC RADIATION TEIJIN LIMITED (JP) 1981-09-29 US claimed
US-4246485-A EPOXY COMPOUND STABILIZER AGAINST DISCOLORATION AND HYDROLYSIS CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1981-01-20 US claimed
US-4117029-A VINYL CHLORIDE POLYE NITTO KASEI CO. LTD. (JP) 1978-09-26 US claimed