Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 14/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764380 | 0.86 | ADRB2 (0.53) | ADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL10467788 | 0.86 | SLC2A1 (0.52) | ADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL9764235 | 0.86 | ADRB2 (0.49) | ADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL9764714 | 0.85 | ADRB2 (0.53) | ADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL9764503 | 0.84 | ADRB2 (0.51) | ADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL9764490 | 0.84 | ADRB2 (0.58) | ADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL9764465 | 0.84 | ADRB2 (0.58) | ADRB2ADRB3ADRB1SLC2A1 | |
| Hydrochloric Acid SCHEMBL9764518 | 0.84 | ADRB2 (0.52) | ADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL9764317 | 0.83 | ADRB2 (0.50) | ADRB2ADRB3ADRB1SLC2A1 | |
| SCHEMBL9764346 | 0.82 | SLC2A1 (0.53) | ADRB2ADRB3ADRB1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181709-B1 | DICHLOROANILINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1990-05-09 | — | — | EP | claimed |
| EP-0181709-A1 | Dichloroaniline Derivatives | GLAXO GROUP LIMITED (GB) | 1986-05-21 | — | — | EP | claimed |
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |
| EP-0181709-B1 | DICHLOROANILINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1990-05-09 | — | — | EP | disclosed |
| EP-0181709-A1 | Dichloroaniline Derivatives | GLAXO GROUP LIMITED (GB) | 1986-05-21 | — | — | EP | disclosed |