Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10488103 | 0.88 | TDP1 (0.45) | TDP1L3MBTL1KCNH2THRATHRB | |
| SCHEMBL9574168 | 0.83 | TDP1 (0.59) | TDP1L3MBTL1CALM1CHRM2SIGMAR1 | |
| SCHEMBL9762727 | 0.82 | TDP1 (0.38) | TDP1L3MBTL1KCNH2THRATHRB | |
| SCHEMBL9763690 | 0.81 | TAAR1 (0.41) | TDP1L3MBTL1KCNH2SLC6A2SLC6A4 | |
| SCHEMBL9574323 | 0.80 | TDP1 (0.63) | TDP1L3MBTL1CALM1MEN1ALDH1A1 | |
| SCHEMBL10465525 | 0.79 | KCNH2 (0.46) | TDP1L3MBTL1KCNH2THRATHRB | |
| SCHEMBL9574237 | 0.79 | TAAR1 (0.39) | TDP1L3MBTL1KCNH2THRATHRB | |
| SCHEMBL9763640 | 0.79 | MEN1 (0.39) | TDP1L3MBTL1KCNH2THRATHRB | |
| SCHEMBL9762902 | 0.79 | CYP4A11 (0.45) | TDP1L3MBTL1KCNH2THRATHRB | |
| SCHEMBL9262777 | 0.79 | IDO1 (0.52) | TDP1L3MBTL1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |