Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763640 | 0.89 | MEN1 (0.39) | CYP4A11MEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL9762727 | 0.85 | TDP1 (0.38) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL9763690 | 0.84 | TAAR1 (0.41) | MEN1KMT2AUSP2ALDH1A1LMNA | |
| SCHEMBL4939834 | 0.82 | LTA4H (0.56) | CYP4A11MEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL20317448 | 0.82 | MEN1 (0.45) | CYP4A11MEN1KMT2AUSP2ALDH1A1 | |
| SCHEMBL9574237 | 0.82 | TAAR1 (0.39) | MEN1KMT2ATHRATHRBTDP1 | |
| SCHEMBL9574249 | 0.81 | IDO1 (0.52) | MEN1KMT2ALMNATDP1L3MBTL1 | |
| SCHEMBL9257411 | 0.81 | IDO1 (0.52) | MEN1KMT2ALMNATDP1L3MBTL1 | |
| SCHEMBL9262777 | 0.81 | IDO1 (0.52) | MEN1KMT2ALMNATDP1L3MBTL1 | |
| SCHEMBL9763639 | 0.81 | RARB (0.50) | CYP4A11MEN1KMT2AALDH1A1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |