Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757089 | 0.89 | TOP2A (0.54) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL9757408 | 0.88 | KCNH2 (0.55) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9757234 | 0.87 | KCNH2 (0.54) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL9757381 | 0.85 | CACNA1F (0.56) | TOP2ATOP2BKCNH2POLBGSK3B | |
| SCHEMBL9757402 | 0.85 | KDM4E (0.59) | TOP2ATOP2BALDH1A1KDM4ELMNA | |
| SCHEMBL9757274 | 0.85 | TOP2A (0.57) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL8094873 | 0.84 | TOP2A (0.60) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL9757498 | 0.83 | TOP2A (0.56) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL9757511 | 0.83 | TOP2A (0.56) | TOP2ATOP2BKCNH2ALDH1A1POLB | |
| SCHEMBL9757420 | 0.83 | TOP2A (0.56) | TOP2ATOP2BKCNH2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |