Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764500 | 1.00 | SLC2A1 (0.33) | SLC2A1NR1H3HSD11B1ADRB2ADRB1 | |
| SCHEMBL9764546 | 0.83 | MAOA (0.37) | NR1H3MAOBAPPMAOAKDM4E | |
| SCHEMBL9764551 | 0.83 | MAOA (0.37) | NR1H3MAOBAPPMAOAKDM4E | |
| SCHEMBL9764436 | 0.82 | KCNH2 (0.44) | — | |
| SCHEMBL9764430 | 0.82 | KCNH2 (0.44) | — | |
| SCHEMBL10417921 | 0.81 | SLC2A1 (0.37) | SLC2A1NR1H3ADRB2MAOBAPP | |
| SCHEMBL10417920 | 0.81 | SLC2A1 (0.37) | SLC2A1NR1H3ADRB2MAOBAPP | |
| SCHEMBL9764330 | 0.81 | MAOB (0.40) | MAOBAPPMAOA | |
| SCHEMBL9764323 | 0.81 | MAOB (0.40) | MAOBAPPMAOA | |
| SCHEMBL9321535 | 0.77 | MAOB (0.37) | NR1H3ADRB2ADRB1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |