Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9764555 | 0.85 | SLC6A4 (0.64) | SLC6A4 | |
| Water SCHEMBL9764559 | 0.85 | SLC6A4 (0.64) | SLC6A4 | |
| SCHEMBL7479356 | 0.82 | SLC6A4 (0.76) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| SCHEMBL7483005 | 0.81 | SLC6A4 (0.61) | SLC6A4 | |
| SCHEMBL4418308 | 0.81 | SLC6A4 (0.61) | SLC6A4 | |
| SCHEMBL7483003 | 0.81 | SLC6A4 (0.61) | SLC6A4 | |
| SCHEMBL4541937 | 0.81 | SLC6A4 (0.61) | SLC6A4 | |
| SCHEMBL7482999 | 0.81 | SLC6A4 (0.61) | SLC6A4 | |
| SCHEMBL13323539 | 0.81 | SLC6A4 (1.00) | SLC6A4KDM4ELMNAPOLBHTR1A | |
| Ammonia Solution, Strong SCHEMBL1122493 | 0.81 | SLC6A4 (0.74) | SLC6A4KDM4ELMNAPOLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066660-A | INDOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1991-11-19 | — | — | US | disclosed |
| EP-0303506-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1989-02-15 | — | — | EP | disclosed |