Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482999 | 1.00 | SLC6A4 (0.61) | SLC6A4 | |
| SCHEMBL9873581 | 0.91 | SLC6A4 (0.63) | SLC6A4 | |
| SCHEMBL9873596 | 0.91 | SLC6A4 (0.63) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL7483189 | 0.88 | SLC6A4 (0.59) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL7483178 | 0.88 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL4563598 | 0.88 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL4563600 | 0.88 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL7804263 | 0.83 | SLC6A4 (0.71) | SLC6A4 | |
| SCHEMBL9764544 | 0.81 | SLC6A4 (0.68) | SLC6A4 | |
| SCHEMBL12006470 | 0.81 | HTR6 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721453-B1 | PROCESS FOR THE PREPARATION OF N-METHYL-3-(1-METHYL-4-PIPERIDINYL)-14-INDOLE-5-ETHANESULPHONAMIDE | GLAXO GROUP LTD (GB) | 2002-11-20 | — | — | EP | disclosed |
| US-5659040-A | Process for the preparation of N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulphonamide | GLAXO GROUP LIMITED (GB) | 1997-08-19 | — | — | US | disclosed |
| EP-0721453-A1 | PROCESS FOR THE PREPARATION OF N-METHYL-3-(1-METHYL-4-PIPERIDINYL)-14-INDOLE-5-ETHANESULPHONAMIDE | GLAXO GROUP LIMITED (GB) | 1996-07-17 | — | — | EP | disclosed |
| WO-1995009166-A1 | PROCESS FOR THE PREPARATION OF N-METHYL-3-(1-METHYL-4-PIPERIDINYL)-14-INDOLE-5-ETHANESULPHONAMIDE | GLAXO GROUP LIMITED (GB) | 1995-04-06 | — | — | WO | disclosed |