SCHEMBL9764585

SCHEMBL9764585

COC(=O)c1ccc2[nH]cc(C3=CCN(C)CC3)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 5/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7485634 0.89 SLC6A4 (0.66) SLC6A4
SCHEMBL7481939 0.87 SLC6A4 (0.70) SLC6A4
Hydrochloric Acid SCHEMBL8786395 0.87 SLC6A4 (0.70) SLC6A4
SCHEMBL9764510 0.87 SLC6A4 (0.65) SLC6A4
SCHEMBL3341152 0.86 SLC6A4 (0.68) SLC6A4
SCHEMBL7490233 0.83 SLC6A4 (0.64) SLC6A4
SCHEMBL2264033 0.83 GABRP (0.60)
SCHEMBL7478018 0.83 SLC6A4 (0.63) SLC6A4
Oxalic Acid SCHEMBL9764549 0.82 SLC6A4 (0.61) SLC6A4
Maleic Acid SCHEMBL9764717 0.81 SLC6A4 (0.55) SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066660-A INDOLE DERIVATIVES GLAXO GROUP LIMITED (GB) 1991-11-19 US disclosed
EP-0303506-A2 Indole derivatives GLAXO GROUP LIMITED (GB) 1989-02-15 EP disclosed