Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818219 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL3155716 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL669556 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL296474 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL4791112 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL8587002 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL3025854 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL3160216 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL14478066 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL3151593 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5779 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6433115-B1 | — | — | None | — | — | US | claimed |
| EP-4380937-A1 | CONJUGATES COMPRISING COVALENT BINDERS FOR TARGETING INTRACELLULAR PROTEINS | Rayzebio, Inc. (US) | 2024-06-12 | — | — | EP | claimed |
| CN-118176194-A | Conjugates comprising covalent binding agents for targeting intracellular proteins | 瑞择生物公司 | 2024-06-11 | — | — | CN | claimed |
| WO-2024109840-A1 | FUSED RING COMPOUND, CONJUGATE THEREOF AND USE THEREOF | 康诺亚生物医药科技（成都）有限公司 | 2024-05-30 | — | — | WO | claimed |
| CN-118079013-A | Condensed ring compound, conjugate and application thereof | 康诺亚生物医药科技（成都）有限公司 | 2024-05-28 | — | — | CN | claimed |
| US-11981611-B2 | Nitrification inhibitors to improve fertilizer efficiency | SOILGENIC TECHNOLOGIES, LLC (US) | 2024-05-14 | — | — | US | claimed |
| CN-117820175-A | Synthesis method of o-amino aryl sulfoxide compound | 山东大学 | 2024-04-05 | — | — | CN | claimed |
| CN-113845399-B | Process for the preparation of ortho-aryl primary amides | 华东理工大学 | 2024-03-22 | — | — | CN | claimed |
| US-20240041889-A1 | COMBINATION THERAPY WITH ADENOSINE RECEPTOR ANTAGONISTS | TEON THERAPEUTICS INC (US) | 2024-02-08 | — | — | US | claimed |
| WO-2024026273-A1 | THERAPY FOR REDUCED OTOTOXICITY FROM CHEMOTHERAPEUTIC AGENT WITH PENTAAZA MACROCYCLIC RING COMPLEX | GALERA LABS, LLC (US) | 2024-02-01 | — | — | WO | claimed |
| US-4886879-A | Process for the preparation of trifluorodichloroethyl-substituted acids and zinc compounds | CIBA-GEIGY CORPORATION (US) | 1989-12-12 | — | — | US | claimed |
| US-4886847-A | Fast-crystallizing polyester compositions | MONTEFIBRE S.P.A. (IT) | 1989-12-12 | — | — | US | claimed |
| US-4869804-A | RADICAL-GENERATING | INSTITUT FRANCAIS DU PETROLE (FR) | 1989-09-26 | — | — | US | claimed |
| EP-0327194-A1 | Synthesis of triarylsulphonium salts | International Business Machines Corporation (US) | 1989-08-09 | — | — | EP | claimed |
| EP-0295654-A2 | Fast-crystallizing polyester compositions | MONTEFIBRE S.p.A. (IT) | 1988-12-21 | — | — | EP | claimed |
| US-4788128-A | Transfer printing medium with thermal transfer dye and infra-red radiation phthalocyanine absorber | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-11-29 | — | — | US | claimed |
| US-4451408-A | Process of preparing sulfonium organosulfonates | THE DOW CHEMICAL COMPANY (US) | 1984-05-29 | — | — | US | claimed |
| EP-0021990-B1 | PROCESS FOR TREATING MIXTURES OF RARE EARTH OXIDES AND GALLIUM OXIDES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1982-12-01 | — | — | EP | claimed |
| US-4318984-A | COMPRISING A PEROXIDASE, A SUGAR OXIDASE AND A CHROMOGEN AND AN OXYGEN FUNCTIONAL GROUP COMPOUND AS EXHANCER | MILES LABORATORIES, INC. (US) | 1982-03-09 | — | — | US | claimed |
| US-3966727-A | Manufacture of phthalo-bis-guanamines | BASF AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | claimed |