Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5610598 | 0.87 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL11061127 | 0.81 | SKP2 (0.39) | ALDH1A1CYP3A4TSHRSKP2KMT2A | |
| SCHEMBL24629974 | 0.79 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL27561633 | 0.79 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL9853387 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL11139083 | 0.77 | CD44 (0.38) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL29611372 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL4968643 | 0.77 | GAA (0.56) | ALDH1A1TSHRTDP1TP53SKP2 | |
| SCHEMBL21548743 | 0.77 | SKP2 (0.37) | ALDH1A1CYP3A4TSHRSKP2KMT2A | |
| SCHEMBL27685433 | 0.77 | ALDH1A1 (0.37) | ALDH1A1CYP3A4TSHRTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017322-A | Interpenetrating polymer network of polysiloxane and polyurethane or polyurea, applied to mold used for boat hull | INTERNATIONAL PAINT PUBLIC LIMITED COMPANY (GB) | 1991-05-21 | — | — | US | disclosed |
| CN-1044673-A | Prevent the method for marine biofouling | INT PAINT PLC (GB) | 1990-08-15 | — | — | CN | disclosed |
| EP-0329375-A1 | Inhibition of marine fouling | COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) | 1989-08-23 | — | — | EP | disclosed |