Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 7/20 | 0.57 |
| ▸ | HTR1B | P28222 | 7/20 | 0.57 |
| ▸ | HTR1A | P08908 | 5/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | HTR2B | P41595 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.57 |
| ▸ | HTR5A | P47898 | 2/20 | 0.57 |
| ▸ | HTR1E | P28566 | 1/20 | 0.57 |
| ▸ | HTR1F | P30939 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.57 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.57 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843293 | 0.85 | HTR1D (0.61) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL8694505 | 0.82 | HTR1D (0.55) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL13805397 | 0.80 | HTR1D (0.63) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| Succinic Acid SCHEMBL6846369 | 0.79 | HTR1D (0.53) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL7475889 | 0.78 | HTR1B (0.52) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| Dimethylamine SCHEMBL8927414 | 0.77 | HTR1D (0.71) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL13926193 | 0.75 | HTR1D (0.76) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL9456487 | 0.74 | HTR1D (0.74) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL2739183 | 0.74 | HTR1D (0.74) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL5918478 | 0.74 | HTR1D (0.74) | HTR1DHTR1BHTR1AHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037845-A | Analgesics; for treatment or prevention of pain due to vasodilation in the cranium | GLAXO GROUP LIMITED (GB) | 1991-08-06 | — | — | US | disclosed |