Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 8/20 | 0.61 |
| ▸ | HTR1B | P28222 | 8/20 | 0.61 |
| ▸ | HTR1A | P08908 | 6/20 | 0.61 |
| ▸ | HTR2A | P28223 | 4/20 | 0.61 |
| ▸ | HTR2B | P41595 | 3/20 | 0.61 |
| ▸ | HTR7 | P34969 | 2/20 | 0.61 |
| ▸ | HTR5A | P47898 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | HTR1E | P28566 | 1/20 | 0.61 |
| ▸ | HTR1F | P30939 | 1/20 | 0.61 |
| ▸ | HTR3A | P46098 | 1/20 | 0.61 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL6846369 | 0.92 | HTR1D (0.53) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL9765113 | 0.85 | HTR1D (0.57) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL8694505 | 0.81 | HTR1D (0.55) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL13551485 | 0.79 | HTR1A (0.64) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL13805397 | 0.78 | HTR1D (0.63) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL9205912 | 0.77 | GABRA1 (0.47) | HTR2AHTR2BHTR2CLMNATHRA | |
| Sumatriptan SCHEMBL14186900 | 0.76 | HTR1A (0.79) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| SCHEMBL7475889 | 0.76 | HTR1B (0.52) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| Sumatriptan SCHEMBL183393 | 0.76 | HTR1A (1.00) | HTR1DHTR1BHTR1AHTR2AHTR2B | |
| Sumatriptan SCHEMBL29450235 | 0.76 | HTR1A (1.00) | HTR1DHTR1BHTR1AHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040068000-A1 | Solid dosage forms; enteric coating; analgesics, headache therapy | GUO MINTONG (US) | 2004-04-08 | — | — | US | claimed |
| WO-1998051301-A1 | USE OF INDOLAMINES AS ANTITHROMBOTIC MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 1998-11-19 | — | — | WO | claimed |
| WO-1998051301-A1 | USE OF INDOLAMINES AS ANTITHROMBOTIC MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 1998-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068000-A1 | Solid dosage forms; enteric coating; analgesics, headache therapy | SI, MAST3, SLC10A2 | HTR1D 37/4885HTR1B 42/4885HTR1A 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.