Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL987047 | 0.91 | TDP1 (0.48) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL8852977 | 0.91 | TDP1 (0.48) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL19581465 | 0.91 | TDP1 (0.48) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL28409050 | 0.91 | TDP1 (0.48) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL4653322 | 0.91 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL18140227 | 0.91 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL2059838 | 0.91 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL5463979 | 0.91 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL5462229 | 0.91 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL475891 | 0.91 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001203-A | UV curable polyorganophosphazene composition | ETHYL CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0334090-A2 | Acrylate cured polyphosphazenes | ETHYL CORPORATION (US) | 1989-09-27 | — | — | EP | disclosed |