Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL19581465 | 1.00 | TDP1 (0.48) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL8852977 | 1.00 | TDP1 (0.48) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL28409050 | 1.00 | TDP1 (0.48) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL5463979 | 0.95 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL476057 | 0.95 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL18140227 | 0.95 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL5462229 | 0.95 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL475891 | 0.95 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL2059838 | 0.95 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL4653322 | 0.95 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099743-B1 | HALOGEN FREE FLAME RETARDANT POLYCARBONATE/THERMOPLASTIC POLYESTER MOLDING COMPOSITIONS WITH POLYMERIC PHOSPHORUS FLAME RETARDANT | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-06-19 | — | — | EP | disclosed |
| US-20190048185-A1 | Halogen Free Flame Retardant Polycarbonate/Thermoplastic Polyester Molding Compositions with Polymeric Phosphorus Flame Retardant | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-02-14 | — | — | US | disclosed |
| EP-3099743-A1 | HALOGEN FREE FLAME RETARDANT POLYCARBONATE/THERMOPLASTIC POLYESTER MOLDING COMPOSITIONS WITH POLYMERIC PHOSPHORUS FLAME RETARDANT | SABIC Global Technologies B.V. (NL) | 2016-12-07 | — | — | EP | disclosed |
| US-20160340507-A1 | Halogen Free Flame Retardant Polycarbonate/Thermoplastic Polyester Molding Compositions with Polymeric Phosphorus Flame Retardant | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-11-24 | — | — | US | disclosed |
| WO-2015116509-A1 | HALOGEN FREE FLAME RETARDANT POLYCARBONATE/THERMOPLASTIC POLYESTER MOLDING COMPOSITIONS WITH POLYMERIC PHOSPHORUS FLAME RETARDANT | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2015-08-06 | — | — | WO | disclosed |
| US-20120279559-A1 | SOLAR MODULES HAVING A POLYCARBONATE BLEND FILM AS THE REAR FACE FILM | BAYER MATERIALSCIENCE AG (DE) | 2012-11-08 | — | — | US | disclosed |
| US-8178603-B2 | Flameproofed impact-modified polycarbonate compositions | BAYER MATERIALSCIENCE AG (DE) | 2012-05-15 | — | — | US | disclosed |
| US-20110003918-A1 | FLAMEPROOFED IMPACT-MODIFIED POLYCARBONATE COMPOSITIONS | BAYER MATERIAL SCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| US-20090163629-A1 | FLAMEPROOFED IMPACT-MODIFIED POLYCARBONATE COMPOSITION | BAYER MATERIALSCIENCE AG (DE) | 2009-06-25 | — | — | US | disclosed |