Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977111 | 0.89 | GRIN2D (0.50) | TDP1KDM4EPOLBCTDSP1L3MBTL1 | |
| SCHEMBL10979888 | 0.83 | TDP1 (0.50) | TDP1KDM4EPOLBCTDSP1L3MBTL1 | |
| SCHEMBL10962625 | 0.81 | MEN1 (0.51) | TDP1KDM4EPOLBCTDSP1L3MBTL1 | |
| SCHEMBL1624471 | 0.80 | TDP1 (0.47) | TDP1KDM4EPOLBCTDSP1L3MBTL1 | |
| SCHEMBL2848439 | 0.80 | TDP1 (0.51) | TDP1KDM4EPOLBCTDSP1L3MBTL1 | |
| SCHEMBL25257569 | 0.80 | TDP1 (0.47) | TDP1KDM4EPOLBCTDSP1L3MBTL1 | |
| SCHEMBL1179747 | 0.80 | TDP1 (0.62) | TDP1KDM4EPOLBCTDSP1L3MBTL1 | |
| SCHEMBL29396391 | 0.80 | TDP1 (0.62) | TDP1KDM4EPOLBCTDSP1L3MBTL1 | |
| SCHEMBL10534522 | 0.79 | ALDH1A1 (0.53) | TDP1KDM4EPOLBCTDSP1L3MBTL1 | |
| SCHEMBL20797428 | 0.79 | TDP1 (0.46) | TDP1KDM4EPOLBCTDSP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041671-A | Process for the preparation 4-chloro-2,5-dimethoxy-aniline | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |