SCHEMBL9765190

SCHEMBL9765190

O=c1[nH]cnc2c1ncn2CC=CO

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 15/20 0.59
PNP P00491 2/20 0.52
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7569894 0.82 HPRT1 (0.58) HPRT1PNPMEN1LMNAKMT2A
SCHEMBL11258920 0.77 HPRT1 (0.69) HPRT1PNP
SCHEMBL1993930 0.76 HPRT1 (0.63) HPRT1PNPMEN1LMNAKMT2A
SCHEMBL455645 0.76 HPRT1 (0.62) HPRT1PNPMEN1LMNAKMT2A
SCHEMBL13667852 0.75 HPRT1 (0.51) HPRT1PNP
SCHEMBL20782416 0.74 HPRT1 (0.65) HPRT1PNP
SCHEMBL11254078 0.73 HPRT1 (0.59) HPRT1PNP
SCHEMBL7812374 0.73 HPRT1 (0.70) HPRT1PNP
SCHEMBL7374581 0.73 HPRT1 (0.64) HPRT1PNP
SCHEMBL6060863 0.73 HPRT1 (0.65) HPRT1PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0355085-B1 A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES CO PHARMA CORPORATION S.R.L. (IT) 1991-09-11 EP claimed
EP-0355085-A1 A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES. CO PHARMA CORP SRL (IT) 1990-02-28 EP claimed
WO-1988005437-A1 A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES CO PHARMA CORPORATION S.R.L. (IT) 1988-07-28 WO claimed
EP-0355085-B1 A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES CO PHARMA CORPORATION S.R.L. (IT) 1991-09-11 EP disclosed
EP-0355085-B1 A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES CO PHARMA CORPORATION S.R.L. (IT) 1991-09-11 EP disclosed
EP-0355085-A1 A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES. CO PHARMA CORP SRL (IT) 1990-02-28 EP disclosed
EP-0355085-A1 A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES. CO PHARMA CORP SRL (IT) 1990-02-28 EP disclosed
WO-1988005437-A1 A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES CO PHARMA CORPORATION S.R.L. (IT) 1988-07-28 WO disclosed
WO-1988005437-A1 A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES CO PHARMA CORPORATION S.R.L. (IT) 1988-07-28 WO disclosed