Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.48 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765390 | 0.85 | ABCB1 (0.61) | KDM4ECYP3A4ALOX15KCNE1KCNQ1 | |
| SCHEMBL9550598 | 0.79 | KDM4E (0.60) | KDM4ECYP3A4ALOX15KCNE1KCNQ1 | |
| SCHEMBL9398457 | 0.78 | KDM4E (0.59) | KDM4ECYP3A4ALOX15KCNE1KCNQ1 | |
| SCHEMBL9398440 | 0.78 | KDM4E (0.59) | KDM4ECYP3A4ALOX15KCNE1KCNQ1 | |
| SCHEMBL9398445 | 0.78 | KDM4E (0.59) | KDM4ECYP3A4ALOX15KCNE1KCNQ1 | |
| SCHEMBL9197725 | 0.77 | ABCC9 (0.53) | KDM4EABCB1ABCC9 | |
| SCHEMBL9197699 | 0.77 | ABCC9 (0.53) | KDM4EABCB1ABCC9 | |
| SCHEMBL9197704 | 0.77 | ABCC9 (0.53) | KDM4EABCB1ABCC9 | |
| SCHEMBL9197710 | 0.77 | ABCC9 (0.53) | KDM4EABCB1ABCC9 | |
| SCHEMBL9197714 | 0.77 | ABCC9 (0.53) | KDM4EABCB1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988723-A | Hypotensive agents, vasodilation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0344747-A1 | Benzopyran derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-06 | — | — | EP | disclosed |