Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765594 | 1.00 | POLB (0.38) | POLBFOLH1GAACASP3PKLR | |
| SCHEMBL9765547 | 0.90 | POLB (0.40) | POLBFOLH1GAAPKLRNAALAD2 | |
| SCHEMBL195323 | 0.90 | POLB (0.40) | POLBFOLH1GAAPKLRNAALAD2 | |
| SCHEMBL9765570 | 0.90 | POLB (0.40) | POLBFOLH1GAAPKLRNAALAD2 | |
| SCHEMBL9765587 | 0.90 | POLB (0.40) | POLBFOLH1GAAPKLRNAALAD2 | |
| SCHEMBL9765550 | 0.90 | POLB (0.40) | POLBFOLH1GAAPKLRNAALAD2 | |
| SCHEMBL9765574 | 0.90 | POLB (0.40) | POLBFOLH1GAAPKLRNAALAD2 | |
| SCHEMBL9765545 | 0.89 | CNR2 (0.40) | POLBFOLH1GAACASP3 | |
| SCHEMBL9799893 | 0.89 | CNR2 (0.40) | POLBFOLH1GAACASP3 | |
| SCHEMBL9765538 | 0.85 | POLB (0.43) | POLBFOLH1GAAPKLRNAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231619-B1 | 3-PHENOXY(OR PHENYLTHIO)CYCLOPENTANECARBONYLAMINO ACID ANALOGUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-03-06 | — | — | EP | claimed |
| EP-0231619-A2 | 3-Phenoxy(or phenylthio)cyclopentanecarbonylamino acid analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-08-12 | — | — | EP | claimed |
| US-5023268-A | Therapy for cerebral edema | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-06-11 | — | — | US | disclosed |